| Scientists' Open Letter on Cryonics Alla mainitut julkaisut eivät ole välttämättä vapaasti saatavilla. Voit kysellä niitä esim. Helsingin yliopiston kirjastosta tai yhdistyksen tapaamisissa.
Katsausartikkeleita.
Merkittäviä julkaisuja.- Ensimmäinen artikkeli, jossa kuvataan kaniinin munuaisen jäähdyttäminen -135 °C:een ja sen toimiminen sulatuksen jälkeen eläimen ainoana munuaisena. Fahy GM, Wowk B, Pagotan R, Chang A, Phan J, Thomson B, Phan L, "Physical and biological aspects of renal vitrification", in: Organogenesis (2009 vol. 5), pg. 167-175.
- First paper showing good ultrastructure of vitrified/rewarmed mammalian brains and the reversibility of prolonged warm ischemic injury in dogs without subsequent neurological deficits, and setting forth the present scientific evidence in support of cryonics: Lemler J, Harris SB, Platt C, Huffman T, in: Annals of the New York Academy of Sciences, (2004 vol. 1019), “The Arrest of Biological Time as a Bridge to Engineered Negligible Senescence", pg. 559-563.
- First paper to
propose cryonics by neuropreservation: Martin
G, in: Perspectives in Biology and Medicine (1971, vol. 14),
“Brief proposal on immortality: an interim solution”, pg.
339.
- First paper showing recovery of a mammalian organ after cooling to -196°C (liquid nitrogen temperature) and subsequent transplantation:
Hamilton R, Holst HI, Lehr HB, in: Journal of Surgical Research (1973, vol
14), "Successful preservation of canine small intestine by freezing", pg. 527-531.
- First paper
showing partial recovery of brain electrical activity after
7 years of frozen storage:
Suda I, Kito K, Adachi C, in: Brain Research (1974, vol. 70),
“Bioelectric discharges of isolated cat brain after revival
from years of frozen storage", pg. 527-531.
- First paper suggesting
that nanotechnology could reverse freezing injury:
Drexler
KE, in: Proceedings of the National Academy of Sciences (1981,
vol. 78), "Molecular engineering: An approach to the development
of general capabilities for molecular manipulation", pg.
5275-5278.
- First paper showing
that large organs can be cryopreserved without structural damage
from ice: Fahy
GM, MacFarlane DR, Angell CA, Meryman HT, in: Cryobiology (1984,
vol. 21), "Vitrification as an approach to cryopreservation",
pg. 407-426.
- First paper showing that
dogs can be recovered after three hours of total circulatory
arrest (“clinical death”) at 0°C (32°F). This supports the reversibility
of the hypothermic phase of cryonics:
Haneda
K, Thomas R, Sands MP, Breazeale DG, Dillard DH, in: Cryobiology
(1986, vol. 23), "Whole body protection during three hours
of total circulatory arrest: an experimental study", pg.
483-494.
- First detailed
discussion of the application of nanotechnology to reverse human
cryopreservation:
Merkle
RC, in: Medical Hypotheses (1992, vol. 39), "The technical
feasibility of cryonics", pg. 6-16.
- First successful
application of vitrification to a relatively large tissue of
medical interest: Song
YC, Khirabadi BS, Lightfoot F, Brockbank KG, Taylor MJ, in:
Nature Biotechnology (2000, vol. 18), "Vitreous cryopreservation
maintains the function of vascular grafts", pg. 296-299.
-
First report of the consistent
survival of transplanted kidneys after cooling to and rewarming from -45°C:
Fahy GM, Wowk B, Wu J, Phan J, Rasch
C, Chang A, Zendejas E, in: Cryobiology (2004 vol. 48), "Cryopreservation
of organs by vitrification: perspectives and recent advances",
pg. 157-78.
- Rigorous
demonstration of memory retention following profound hypothermia,
confirming theoretical expectation and clinical experience.
Alam HB, Bowyer MW, Koustova E, Gushchin V, Anderson D, Stanton K,
Kreishman P, Cryer CM, Hancock T, Rhee P, in: Surgery (2002, vol. 132),
"Learning
and memory is preserved after induced asanguineous hyperkalemic
hypothermic arrest in a swine model of traumatic exsanguination", pg. 278-88.
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